先后于太阳成集团tyc151国家级生物医学材料研究中心、华西口腔疾病防治全国重点实验室求学并留实验室工作。具备生物、材料、骨/牙疾病等多学科背景，擅长依托转基因敲除鼠技术，专注骨质疏松、牙周疾病及血管钙化的基础医学研究。主持2项国家级科研项目，积极参与十余项团队的科研项目，发表SCI论文十余篇。坚持在科研一线鼓励并支持本科同学开展实验，培养科研思维，并有多篇SCI文章发表。

1. Guanyue Su^#,Demao Zhang^#, Tiantian Li, Tong Pei , Jie Yang, Shasha Tu, Sijun Liu, Jie Ren, Yaojia Zhang, Mengmeng Duan, Xinrui Yang, Yang Shen, Chenchen Zhou, Jing Xie*, Xiaoheng Liu*. Annexin A5 derived from matrix vesicles protects against osteoporotic bone loss via mineralization. Bone Res. 2023 Nov 9;11(1):60.

2. Xianchun Ruan, Jinning Gu, Mingyang Chen, Fulin Zhao, Munire Aili,Demao Zhang*. Multiple roles of ALK3 in osteoarthritis. Bone & Joint Research. 2023 Jul 3;12(7):397-411.

3. Mingyang Chen, Fulin Zhao, Wenlin Chu,Mingru Bai*,Demao Zhang*, A review of tamoxifen administration regimen optimization for Cre/loxp system in mouse bone study. Biomed Pharmacother. 2023 Sep;165:115045.

4. Hongcan Huang, Jing Xie, Jieya Wei, Siqun Xu,DemaoZhang*,Xuedong Zhou*. Fibroblast growth factor-8 (FGF-8) upregulates gelatinases expression in chondrocytes through nuclear factor-κB p65. Journal of Bone and Mineral Metabolism, 2023, 41(1): 17-28.

5. Xinyue Pan, Caixia Pi, Xianchun Ruan, Hanhua Zheng,Demao Zhang*, Xiaoheng Liu*. Mammalian Sirtuins and Their Relevance in Vascular Calcification. Frontiers in Pharmacology, 2022 May 23;13:907835.

6. Zhixing Niu, Guanyue Su, Tiantian Li, Hongchi Yu, Yang Shen,Demao Zhang*and Xiaoheng Liu*. Vascular Calcification: New Insights Into BMP Type I Receptor A. Frontiers in Pharmacology, 2022 Apr 6:13:887253

7. Mingru Bai, Huiyu Chen, Zhaowei Zhang, Xiaoyu Liu,Demao Zhang*, Chengling Wang*.Substrate stiffness promotes dentinogenesis via LAMB1–FAK–MEK1/2 signaling axis[J]. Oral Diseases, 2022. 00, 1– 13.

8. Demao Zhang^#, Xin Li^#, Caixia Pi, Linyi Cai, Yang Liu, Wei Du, Wenbin Yang*, Jing Xie*, Osteoporosis-decreased extracellular matrix stiffness impairs connexin 43-mediated gap junction intercellular communication in osteocytes.Acta Biochimica et Biophysica Sinica, 2020 52.5: 517-526.

9. Demao Zhang, Chenchen Zhou, Qingxuan Wang, Linyi Cai, Wei Du, Xiaobing Li, Xuedong Zhou, Jing Xie*. Extracellular Matrix Elasticity Regulates Osteocyte Gap Junction Elongation: Involvement of Paxillin in Intracellular Signal Transduction. Cellular Physiology and Biochemistry, 2018, 51(3): 1013-1026.

10. Demao Zhang^#,Junjun Jing^#, Feng Lou^#, Ruimin Li, Yilin Ping, Fanyuan Yu, Fanzi Wu, Xiao Yang, Ruoshi Xu, Feifei Li, Ke Wang, Mingru Bai, Caixia Pi, Jing Xie*, Liwei Zheng, Ling Ye, Xuedong Zhou*. Evidence for excessive osteoclast activation in SIRT6 null mice. Scientific Reports, 2018, 8(1): 10992.

11. Demao Zhang, Dixin Cui, Ruoshi Xu, Yachuan Zhou, Liwei Zheng, Peng Liu, Xuedong Zhou*. Phenotypic research on senile osteoporosis caused by SIRT6 deficiency. International Journal of Oral Science, 2016, 8(2), 84-92.

12. ChenChen Zhou, RuoShi Xu, ZuPing Wu, ZhaoWei Zhang, Quan Yuan, ShuJuan Zou, Jing Xie,Demao Zhang*, Osteogenesis, Osteoclastogenesis and their Crosstalk in Lipopolysaccharide-induced Periodontitis in Mice. The Chinese Journal of Dental Research. 24.1 (2021): 33-39.

13. Peng Liu^#, Yilin Ping^#, Meng Ma^#,Demao Zhang^#, Connie Liu, Samir Zaidi, Song Gao, Yaoting Ji, Feng Lou, Fanyuan Yu, Ping Lu, Agnes Stachnik, Mingru Bai, Chengguo Wei, Liaoran Zhang, Ke Wang, Rong Chen, Maria I. New, David W. Rowe, Tony Yuen, Li Sun, Mone Zaidi*. Anabolic actions of Notch on mature bone. Proceedings of the National Academy of Sciences of the United States of America, 2016, 113(15), E2152-E2161.

14. Luling Wang, Caixia Pi, Jianxun Sun, Yujia Cui, Linyi Cai, Yuanchen Lan, Jinning Gu, linfeng Liu, Geru Zhang, Lianyang Guo, Zhaowei Zhang, Qiang Guo, Liwei Zheng, Jing Xie,Demao Zhang*, Xuedong Zhou*. The alteration of A disintegrin and metalloproteinase with thrombospondin motifs (ADAMTS) in the knee joints of osteoarthritis mice. Journal of Histotechnology, 2021 Jun;44(2):99-110.